COVID-19 Biomarkers Identified in Children


The inflammatory response in a number of organs was primarily seen amongst Black youngsters and the median age of the sufferers was 9 years.

‘In youngsters, COVID-19 causes multisystem inflammatory response syndrome and is deadly.

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“It is crucial to improve our understanding of MIS-C in the current environment, given reports of rising rates of children being hospitalized with COVID-19 in the U.S. and the return of many students to school for the fall term,” says Moshe Arditi, director of the Pediatric Infectious Diseases Division at Cedars-Sinai.

A research was carried out amongst a small group of sufferers to see the pathogenic pathway in MIS-C. In this, the proteins within the blood act as biomarkers to establish the severity of the an infection and it additionally helps to offer correct therapy.

The inflammatory response in youngsters is much like cytokine storm which is normally deadly amongst covid-19 sufferers. The signs of the situation are persistent fever, gastrointestinal issues, cardiovascular issues (sudden coronary heart shock and coronary heart muscle irritation), respiratory issues and neurological issues. These issues are life threatening and can even result in bacterial infections.

“We deployed an array of advanced techniques, including proteomics, RNA sequencing and analyses of antibodies and immune system signaling,” says Van Eyk, professor of Cardiology, Biomedical Sciences and Pathology and Laboratory “By combining forces, we are better able to accelerate scientific discoveries to keep pace with the rapidly evolving pandemic and to inform clinical decisions.”

Further investigations are wanted to validate the findings.

Source: Medindia

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