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Label Changes May Not Prevent Acetaminophen Overdoses

In Canada, the % of acetaminophen-related accidents associated to unintended overdose in Canada elevated from 27% in 2006 to 45% in 2011.

To improve consciousness of potential hurt, product label adjustments had been made in Canada in October 2009 to warn of the danger of potential liver harm. In 2016, they had been up to date with further labeling for protected dosing and to determine merchandise containing acetaminophen.

In this examine of greater than 12 000 hospital admissions for unintended acetaminophen overdose in 9 provinces and three territories in Canada between 2004 and 2020, researchers discovered there was no impression from the up to date labeling on admissions


The authors recommend these findings have a number of implications for public well being.

Because of the human and economic burden imparted by accidental acetaminophen overdoses, additional measures for preventing these episodes are required, beyond those that attempt to inform consumers about the potential risks of acetaminophen through product labels and package inserts.

This is especially important when considered in light of previous research that showed that fewer than 50% of patients regularly read labeled instructions for use of over-the-counter analgesics, and only 26% read the active ingredients before first use.”

As nicely, 4.5% to six% of sufferers exceed the utmost every day dosage, maybe as a result of acetaminophen is present in different cough and chilly medicines, in line with research from the United Kingdom and the United States.

Suggestions for stopping unintended acetaminophen overdoses embrace elimination of acetaminophen from different nonanalgesic over-the-counter medicines, discontinuing opioid-acetaminophen mixture merchandise and limiting most doses of 325 mg per unit.

Source: Medindia

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