According to Martin den Heijer- professor at Amsterdam UMC “Gender-affirming hormone treatment is thought to be safe, and most causes of death in the cohort were not related to this. However, as there is insufficient evidence at present to determine their long-term safety, more research is needed to fully establish whether they in any way affect mortality risk for transgender people.”
The examine was carried out on 4,568 transgender individuals (2,927 transgender girls and 1,641 transgender males) who had been receiving gender-affirming hormone therapy. The knowledge was collected primarily based on age, kind of therapy, smoking habits and medical historical past. The common age to start out the hormone therapy was 30 years in transgender girls and 23 years in transgender males.
The mortality threat was double amongst transgender girls in comparison with males generally Dutch inhabitants and thrice better in comparison with cis girls. The reason behind demise in transgender girls was due to heart problems (2.6%), lung most cancers (3.1%), and HIV an infection (8.7%).The mortality threat in transgender males was much like cis males however twice increased in comparison with cis girls.
“We found that most suicides and deaths related to HIV occurred in the first decades we studied, suggesting that greater social acceptance and access to support, and improved treatments for HIV, may have played an important role in reducing deaths related to these causes among transgender people in recent years. It was surprising that mortality risk was higher in transgender people who started gender-affirming hormone treatment in the past two decades, but this may be due to changes in clinical practice. In the past, health care providers were reluctant to provide hormone treatment to people with a history of co morbidities such as cardiovascular disease. However, because of the many benefits of enabling people to access hormone therapy, nowadays this rarely results in treatment being denied.” Says christle de blok.
There had been few limitations for the examine
The reason behind demise was documented nicely however different components that contribute to mortality weren’t recorded
Analysis on transgender youth was not attainable as they began the hormone remedy at totally different levels of puberty and at totally different ages.
The examine targeted on transgender individuals who acquired therapy in Netherlands and greater than 90% had been White.
The mortality price in transgender individuals might be decreased by rising social acceptance, correct therapy and monitoring for heart problems, tobacco use and HIV.