Prof Durgesh Dwivedi, division of radiodiagnosis, who led the research, mentioned, “We have developed a non-invasive method using Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI). Our initial study on a small sample size has found the method to be effective. Now an advanced study is being done on a larger sample to establish its efficacy.”
“It is a first-of-its-kind method in the world for detecting kidney cancer. It will also suggest which medicines can be given to patients with least side effects. The findings of our pioneering research study have recently been published in the high-impact and peer reviewed International Journal of Cancer and Clinical Research,” he knowledgeable.
According to Prof Dwivedi, historically, biopsy is finished to substantiate most cancers in kidney cells. In this process, tissues of the tumour on the kidney are taken out by inserting a needle. However, since most cancers sufferers are immune-compromised, there are probabilities of an infection in inserting a needle within the organ because it cuts into the tissues.
On the opposite hand, DCE-MRI — a sophisticated model of MRI — is a mixture of non-invasive imaging, genomics and radiomix.
“Simultaneously, these patients also underwent biopsy tests, the results of which confirmed cancer. This proved that the diagnosis done through DCE-MRI is as effective as biopsy.
The study is now being conducted on a larger sample of patients to further consolidate our findings.
As part of the study, experts also conducted DCE-MRI of 19 other patients who had already been diagnosed with cancer through biopsy and were under medication for some time.
The objective of this research was to examine how effective drugs and therapies (anti-angiogenic and immune) are in preventing growth of cancer cells in these patients.
“The DCE-MRI outcomes had been analysed together with genetics and observable bodily properties of the sufferers. The minute observations not solely facilitated identification of biomarkers required to diagnose most cancers but additionally helped in analyzing whether or not a drug/remedy is decreasing or rising irritation in a affected person or inflicting any unwanted effects,” mentioned Prof Dwivedi.
Source: IANS
