Oct. 22, 2021 — Pfizer says its vaccine for youngsters is 90% efficient at stopping COVID-19 infections.
The Pfizer vaccine for teenagers ages 5 to 11 is 10 micrograms, roughly one-third of the dose given to adolescents and adults.
In knowledge introduced to the FDA forward of the company’s evaluate of its photographs for youngsters, the corporate described the interim outcomes of two ongoing research testing the security and effectiveness of its 10-microgram photographs.
The vaccine effectiveness knowledge comes from a research of greater than 2,000 youngsters ages 5 to 11. Two-thirds of the kids have been randomly assigned to obtain a child-sized dose of the Pfizer-BioNTech vaccine, whereas the opposite third was sorted into the placebo group.
The research received underway because the Delta variant grew to become dominant world wide. As of the primary week of October, 16 members within the placebo group had gotten a symptomatic, lab-confirmed COVID-19 an infection, in contrast with simply three who caught COVID within the vaccinated group.
According to the corporate’s evaluation of its personal research, uncomfortable side effects seen within the research have been almost all delicate. The most typical aspect impact reported was ache on the website of the shot. Kids within the group that obtained the vaccine additionally had fatigue, complications, fever, and chills at greater charges than have been seen within the placebo group. These have been most typical after the second dose. Some pores and skin reactions have been seen within the research, like itching and rashes, however these have been principally delicate and went away inside a couple of days.
Kids additionally might have swollen lymph nodes after their vaccinations, as adults generally do, however these reactions have been non permanent.
One youngster developed a tic, a recurring involuntary muscle twitch or vocal sound, that got here one week after their second dose of the vaccine. It was judged by research investigators to be associated to the vaccine. The firm says it was going away by the point the research was being revealed.
Reassuringly, no circumstances of coronary heart irritation referred to as myocarditis have been discovered within the research. Myocarditis is uncommon and non permanent, however it requires hospital care. The highest charges of myocarditis have been seen in males youthful than 30. That group has a danger of about 11 circumstances for each 100,000 doses given, in response to a latest research within the New England Journal of Medicine.
